Adding to its recent endovascular aortic repair
(EVAR) innovations, Medtronic, Inc. (NYSE: MDT), today announced the U.S. launch of
the Talent Abdominal Stent Graft on the Xcelerant Hydro Delivery System.

EVAR is a treatment for aortic aneurysm, a dangerous bulge or weakening in the body’s
main artery that can rupture with fatal consequences if left untreated. In the United
States, abdominal aortic aneurysms – the most common type – are responsible for
approximately 15,000 deaths annually. Worldwide, it is estimated that more than one
million people are living with undiagnosed aortic aneurysms, and that 95 percent of
these could be successfully treated if detected before rupture.

EVAR involves the navigation of a stent graft, via the body’s arteries, to the aorta. The
stent graft is then deployed to create a reinforced tube within the aorta, reducing
pressure on the aneurysm and the risk of rupture. EVAR is a minimally-invasive alternative to open surgical repair.

The Xcelerant Hydro Delivery System features a hydrophilic coating which attracts and
holds water at the device surface to reduce friction. The coating is designed to aid
navigation through the femoral and iliac arteries en route to the aorta.

“The combination of the Xcelerant Hydro Delivery System and the Talent Abdominal
Stent Graft represents another major step forward for the treatment of patients with
abdominal aortic aneurysms,” said Dr. Manish Mehta of Albany Medical College and
Albany Medical Center Hospital in New York. “The hydrophilic coating takes
deliverability to a new level and gives endovascular interventionalists like me greater
control over the deployment of this excellent stent graft, which has no equal in terms of
sizes and profile. Taken together, these technologies simplify the procedure and
enhance patient care – a powerful combination indeed.”

“The Xcelerant Hydro Delivery System again demonstrates Medtronic’s innovation in
the field of EVAR,” said Tony Semedo, vice president and general manager of
Endovascular Innovations at Medtronic. “The launch of the Talent stent grafts earlier
this year made EVAR available to significantly more patients than possible with earlier
technologies. Now, by introducing the Talent Abdominal Stent Graft on the Xcelerant
Hydro Delivery System in the United States, we have enhanced navigation. All of these
innovations benefit physicians and patients alike.”

A pioneer of EVAR, Medtronic has been an innovator and leader in the stent graft
industry for over a decade. Its history includes more than 150,000 patients treated with
stent grafts dating back to 1995. Medtronic offers the broadest portfolio of aortic stent
grafts. The AneuRx AAAdvantage ® and Talent Abdominal Stent Grafts with the
Xcelerant Hydro Delivery System and the Talent Thoracic Stent Graft with the Xcelerant
Delivery System are commercially available in the U.S. The Valiant ® Thoracic Stent Graft and the Endurant ® Stent Graft Systems are commercially available only outside
the U.S. The Reliant ® Stent Graft Balloon Catheter is commercially available worldwide.

About Medtronic

Medtronic, Inc., headquartered in Minneapolis, is the global
leader in medical technology – alleviating pain, restoring health and extending life for
millions of people around the world.

Any forward-looking statements are subject to risks and uncertainties such as those
described in Medtronic’s Annual Report on Form 10-K for the year ended April 25, 2008. Actual results may differ materially from anticipated results.

Medtronic